Oligo-heteropolysaccharides having a heparin-like activity method for their preparation and pharmaceutical compositions based thereon
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United States of America Patent
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Jul 12, 1988
Grant Date -
N/A
app pub date -
Jan 7, 1986
filing date -
Aug 9, 1977
priority date (Note) -
Expired
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Abstract
A oligo-heteropolysaccharide is disclosed which is very active against thrombotic syndromes and is prepared starting from depolymerized heparin fractions wherein the active groups, more particularly the sulfuric groups have been reconstituted by reacting a heparin fraction with a mol wt from 2,000 to 5,000 with the sulfotrioxide of a nitrogeneous organic base such as pyridine and trimethylamine. The method of preparation is also disclosed.
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