Ferrioxamine paramagnetic contrast agents for MR imaging
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United States of America Patent
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Jul 19, 1988
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N/A
app pub date -
Feb 6, 1986
filing date -
Jan 4, 1985
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Abstract
In the NMR imaging of a subject comprising administering to such subject a composition containing an image-modifying effective amount of an image enhancer, permitting the enhancer to move through the subject, and after a time interval taking an NMR image of the subject, the improvement which comprises employing as said enhancer a complex of an oxamine and a polyvalent paramagnetic metal, e.g. ferrioxamine. Novel complexes of trihydroxamic acids, optionally N-acylated, with polyvalent metals other than iron, are also described.
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