Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders

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United States of America Patent

PATENT NO 4758431
SERIAL NO

06428900

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Abstract

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A novel system and method for treating ischemic neurologic tissue is disclosed wherein an oxygenated nutrient emulsion is circulated through at least a portion of the cerebospinal pathway. The nutrient emulsion contains an oxygenatable non-aqueous component, an aqueous nutrient component, an emulsification component, and other components which render physiologic acceptability of the nutrient emulsion. Methods for producing the nutrient emulsion and a system for delivering that emulsion to the cerebrospinal pathway are also disclosed. Additionally, novel diagnostic methods for diagonising the physiologic state of hypoxic-ischemic and other diseased neurologic tissue during treatment are provided.

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Patent Owner(s)

Patent OwnerAddress
THOMAS JEFFERSON UNIVERSITYPHILADELPHIA PA 19107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Osterholm, Jewell L Radnor, PA 22 1238

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