Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists

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United States of America Patent

PATENT NO 4760069
SERIAL NO

06778800

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Abstract

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A potent, selective opioid receptor agonist or antagonist exhibiting properties useful for a long-acting analgesic or opiate abuse treatment agent or appetite suppressant having the general formula: ##STR1## wherein R is methyl, cyclopropylmethyl or allyl, and R.sub.1 is an unsubstituted or substituted aryl, aralkyl, heteroaryl, heteroaralkyl or a cycloalkyl group with or without a heteroatom like S,O,N; and the pharmaceutically acceptable salts thereof.

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Patent Owner(s)

Patent OwnerAddress
NOVA PHARMACEUTICAL CORPORATION 5210 EASTERN AVENUE BALTIMORE MD 21224-2788 A CORP OFDE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mavunkel, Babu J Baltimore, MD 24 471
Rzeszotarski, Waclaw J Millersville, MD 19 408

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