Basic formulations of quinolonecarboxylic acids
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United States of America Patent
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Sep 20, 1988
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N/A
app pub date -
Sep 14, 1987
filing date -
Jan 5, 1985
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Expired
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Abstract
Improvement in the parenteral administration of a carboxylic acid of the formula ##STR1## in which X is N, C--H or C--F, Z is O or Ch.sub.2, R.sub.1 is hydrogen, methyl, ethyl or .beta.-hydroxyethyl, R.sub.2 is cyclopropyl, 2-fluoroethyl or ethyl, R.sub.3 is hydrogen or methyl, and R.sub.4 is H or methyl, is achieved through the administration of the basic salt of the acid (I, II). Surprisingly the basic salts are suitable and stable.
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