Process for the selective preparation of isosorbide-2-mononitrate from isosorbide-2,5-dinitrate
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United States of America Patent
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Oct 11, 1988
Grant Date -
N/A
app pub date -
Nov 7, 1986
filing date -
May 10, 1985
priority date (Note) -
Expired
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Abstract
A process for the preparation of isosorbide-2-mononitrate (I) ##STR1## from isosorbide-2,5-dinitrate (II) ##STR2## The isosorbide-2,5-dinitrate (II) is treated, in a reaction medium consisting of an aqueous organic solvent, with salts of metals of low oxidation state. Isosorbide-2-mononitrate (I) is obtained with high selectivity.
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