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Abstract

A pyridine compound of the formula I ##STR1## in which R.sup.1 and R.sup.2 independently of each other represent hydrogen or alkyl having from 1 to 4 carbon atoms, R.sup.3 represents hydrogen or alkyl having up to 2 carbon atoms and A represents alkylene having 2 to 4 carbon atoms, n is O or 1, Z is a group of the formula Za, Zb or Zc ##STR2## in which either R.sup.4 is hydrogen and R.sup.5 is phenyl or cinnamyl or R.sup.4, R.sup.5, R.sup.7 and R.sup.8 independently of each other are pyridyl, phenyl or phenyl which is substituted by up to 2 equal or different substituents from the group halogen and alkoxy having up to 2 carbon atoms, R.sup.6 is hydrogen or hydroxy and X is hydrogen, a cyano, amino or nitro group or the group --CO--R.sup.9, in whcih R.sup.9 is hydroxy or alkoxy having from 1 to 4 carbon atoms, and the physiologically tolerable salts of these compounds. The invention also relates to a process for the manufacture of such compounds and to their use in pharmaceutical compositions.

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First Claim