Mucopolysaccharides having biological properties, preparation and application thereof as drugs
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United States of America Patent
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Feb 14, 1989
Issued Date -
N/A
app pub date -
Feb 19, 1985
filing date -
Nov 6, 1978
priority date (Note) -
Expired
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Abstract
Mucopolysaccharides biologically active and more specific than heparin, particularly with respect to the blood factor Xa. These mucopolysaccharides may be obtained by partial depolymerization, under controlled conditions, of heparin, by the action of a chemical agent such as nitrous acid. The conditions implemented allow the preparation of mucopolysaccharides having a USP titer lower than that of the starting heparin and a Yin-Wessler titer at least equal to that of said heparin. These products may be used particularly as antithrombotic drugs.
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