Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration

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United States of America Patent

PATENT NO 4806341
SERIAL NO

06903273

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Transdermal absorption morphinan narcotic analgesic or antagonist pharmaceutical polymer matrix dosage units have been developed which comprise a backing layer and an adjoining layer of a solid polymer matrix in which minimum effective doses of morphinan narcotic analgesic or antagonist pharmaceuticals are microdispersed and transdermally supplied. A presently preferred analgesic is hydromoprhone. The dosage units use a biologically acceptable adhesive polymer means to adhere the dosage units to the subject to be treated. The polymer matrix has dispersed one or more skin permeation enhancers. The invention also provides a process for transdermal absorption of said pharmaceuticals in at least minimum dosage amounts.

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Patent Owner(s)

  • RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;RUTGERS, STATE UNIVERSITY OF NEW JERSEY, THE, OLD QUEEN BUILDING, SOMERSET AND GEORGE STREETS, NEW BRUNSWICK, NJ 08903

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chiang, Chin-Chih Piscataway, NJ 20 344
Chien, Yie W North Brunswick, NJ 18 1419
Tojo, Kabuji Highland Park, NJ 1 264

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