Inhibition of HTLV-III by exogenous oligonucleotides
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United States of America Patent
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Feb 21, 1989
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May 23, 1986
filing date -
May 23, 1986
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Expired
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Abstract
Inhibition of HTLV-III by adminstration of an oligonucleotide complementary to highly conserved regions of the HTLV-III genome necessary for HTLV-III replication and/or gene expression is described, as are oligodeoxynucleotide sequences which are complementary to those regions, methods of inhibiting HTLV-III replication and gene expression and methods of determining the presence or absence of HTLV-III virus in samples such as blood, saliva, urine and tears.
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