Method and compositions for reducing neurotoxic injury
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United States of America Patent
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Feb 21, 1989
Grant Date -
N/A
app pub date -
Nov 25, 1986
filing date -
Nov 25, 1986
priority date (Note) -
Expired
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Abstract
A method for reducing adverse effects of neurotoxic injury, which comprises administering to a patient susceptible to neurotoxic injury an effective amount, sufficient to reduce the injury, of a compound which is an enantiomer of an analgesic opioid agonist or antagonist, preferably an opiate agonist having a ring system of the following stereochemistry, which shows only carbon and nitrogen atoms in the rings: ##STR1## The dextrorotatory opiates, dextrorphan and dextromethorphan, are particularly suitable for use in the method of the invention.
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