Volume independent diagnostic device
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United States of America Patent
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-
Mar 7, 1989
Grant Date -
N/A
app pub date -
Jun 19, 1987
filing date -
Jun 19, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A process and device for quantitative determination of analyte concentrations in liquid samples. The device includes one or more bibulous matrices constructed and arranged to essentially eliminate sample volume sensitivity from analyte determinations. In accordance with the present invention, the device includes one or more test reagent-treated bibulous matrices covered at least partially by an impermeable coating or film. A liquid sample is applied to the uncovered portion of the bibulous matrix such that the liquid sample is metered into the bibulous matrix by the impermeable coating or film. The sample chromatographs through the bibulous matrix until the matrix is saturated with liquid. The process is essentially sample volume independent, providing more uniform and accurate quantitative analyte determinations.
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