4-aminobutanoic acid derivatives, process of preparation and use thereof
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United States of America Patent
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Mar 21, 1989
Issued Date -
N/A
app pub date -
Dec 2, 1986
filing date -
Dec 2, 1985
priority date (Note) -
Expired
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Abstract
The invention relates to new (4S)-4-aminobutanoic acid derivatives of general formula: ##STR1## in which: R represents an N-protective group, R.sub.1 represents hydrogen, an alkali metal atom such as lithium, sodium or potassium or a liabile group, R.sub.2 represents a group of formula: ##STR2## in which W represents hydrogen, a hydroxy group or an alkyl radical containing from 1 to 4 carbon atoms or an alkoxy radical containing from 1 to 4 carbon atoms, and to a process for the preparation of the said derivatives. The 4-aminobutanoic acid derivatives according to the invention are useful as synthesis intermediates for the preparation of peptides derived from statin analogues.
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