Method of inhibiting tumor growth sensitive to CIF-.beta.treatment
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United States of America Patent
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Mar 28, 1989
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N/A
app pub date -
Nov 7, 1986
filing date -
Nov 7, 1986
priority date (Note) -
Expired
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Abstract
Polypeptides called cartilage-inducing factors (CIFs) that are found in bone and have heretofore been identified as having in vitro cartilage-inducing activity. TGF-.beta. activity, and anti-inflammatory activity have now been found to possess potent oncostatic activity. The CIFs showed oncostatic activity on human and animal tumors, including carcinomas, adenocarcinomas, lymphomas, and melanomas.
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