Crystalline, anhydrous sigma-form of 2-(4-(2-furoyl)-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxy-quinazoline hydrochloride and a process for its preparation

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United States of America Patent

PATENT NO 4816455
SERIAL NO

07021161

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Abstract

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A new anhydrous crystalline form of prazosine hydrochloride characterized by the following bands in the infra-red spectrum in potassium bromide is described: 3445 cm.sup.-1 (2.90 .mu.m), 1010 cm.sup.-1 (9.90 .mu.m) (duplet), and 768 cm.sup.-1 (13.03 .mu.m). This new form is distinguished by its surprisingly great stability in storage compared with known polymorphous forms of prazosine.

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Patent Owner(s)

Patent OwnerAddress
HEUMANN PHARMA GMBH & COHEIDELOFFSTR 18-20 D-8500 NUREMBERG 1 GERMANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahrens, Kurt H Nuremberg, DE 25 176
Grafe, Ingomar Nuremberg, DE 13 137
Schickaneder, Helmut Eckental, DE 40 303

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