Recombinant immunoglobin preparations

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United States of America Patent

PATENT NO 4816567
SERIAL NO

06483457

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Abstract

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Altered and native immunoglobulins, including constant-variable region chimeras, are prepared in recombinant cell culture. The immunoglobulins contain variable regions which are immunologically capable of binding predetermined antigens. Methods are provided for refolding directly expressed immunoglobulins into immunologically active form.

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Patent Owner(s)

Patent OwnerAddress
CITY OF HOPE A CORP OF CA1500 EAST DUARTE RD DUARTE CA 91010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cabilly, Shmuel Monrovia, CA 15 5083
Heyneker, Herbert L Burlingame, CA 37 6295
Holmes, William E Pacifica, CA 24 5457
Riggs, Arthur D La Verne, CA 26 5957
Wetzel, Ronald B San Francisco, CA 5 4970

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