Method of concentrating and detecting biomolecules and cells
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United States of America Patent
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Apr 18, 1989
Grant Date -
N/A
app pub date -
Sep 23, 1985
filing date -
Jan 25, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method of detecting biological substances having affinity properties by passing the substance to be detected in a flow over a solid surface to which surface a second substance, to which the substance to be detected shows affinity, is attached, so that the two substances form a complex and give enrichment of the substance to be detected. The enrichment is obtained when the fluid volume passing the active surface is many times larger than the volume in contact with the active surface. A means for detecting biological substances consisting of a flow of a fluid sample of the substance to be detected generated via a pump over a solid surface to which another substance, to which the first substance to be detected shows affinity, is attached, so that a complex is formed of the two substances and gives enrichment of the substance to be detected.
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