Nucleotide analogs for nucleic acid labeling and detection

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United States of America Patent

PATENT NO 4828979
SERIAL NO

06669334

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Abstract

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Nucleotide analogs, modified by the attachment at hydrogen bonding positions of linker groups, that is, the 6-position of adenine, 4-position of cytosine, and 2-position of guanine, are prepared. Such analogs, alone or with reporter groups attached, may be incorporated into DNA probes which effectively hybridize to target DNA.

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LIFE TECHNOLOGIES INC A CORP OF OHIONot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gebeyehu, Gulilat Silver Spring, MD 65 2481
Klevan, Leonard Washington, DC 19 560
Rao, Prasad Y Damascus, MD 1 291

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