Polymer particles and latices thereof for the immobilization of biologically active substances
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United States of America Patent
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May 9, 1989
Issued Date -
N/A
app pub date -
Jul 20, 1987
filing date -
Apr 29, 1981
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Polymer particles dispersible to form a latex and latices of such polymer particles, said particles being adaptable to the fixing or bonding thereto of a biologically active substance and having a core-shell construction wherein the polymer material of the core determines the stability of the form of the latex particles and their redispersibility, and the material of the shell (1) is so hydrophilic that it would be completely or largely water soluble if it were not anchored to the core material and/or crosslinked, (2) contains functional groups which are suitable for the covalent fixation or bonding of biological active substances, and (3) in an anhydrous condition has a T.sub..lambda.max from 20.degree.-250.degree. C., depending on its composition, and methods for bonding a biologically active substance to such particles, for example to prepare a diagnostic reagent.
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