Controlled release pharmaceutical composition
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United States of America Patent
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-
May 30, 1989
Grant Date -
N/A
app pub date -
May 19, 1987
filing date -
Jun 5, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C.sub.12 -C.sub.36 fatty alcohol and a polyalkylene glycol. Preferably the first substance is a cyclodextrin, especially a beta-cyclodextrin, while the second substance is a C.sub.14 -C.sub.22 fatty alcohol, especially stearyl alcohol, cetyl alcohol, cetostearyl alcohol or myristyl alcohol. The matrix may also contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose.
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