Method of chain combination
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United States of America Patent
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May 30, 1989
Grant Date -
N/A
app pub date -
Jun 23, 1986
filing date -
Jun 23, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Production of human relaxin or novel human relaxin analogs by combination of a human relaxin A-chain and B-chain comprises combining the reduced form of the human relaxin A-chain and the reduced form of the human relaxin B-chain in an aqueous medium having a pH of about 7.0 to 12 at room temperature, under conditions that are mildly denaturing for the relaxin B-chain such that the human relaxin or novel human relaxin analog can be formed.
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