Process for the synthesis of phenoxyalkane derivatives
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United States of America Patent
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Jun 6, 1989
Grant Date -
N/A
app pub date -
Mar 31, 1982
filing date -
Aug 21, 1980
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention concerns a process for the synthesis of a compound of formula I ##STR1## wherein: U and V may be chosen from a range of substituents including hydrogen, halogen, alkyl and alkoxy; R.sup.1 and R.sup.2 may be chosen from a range of substituents including hydrogen and alkyl; n is 0, 1 or 2; and W may be chosen from a range of substitutents including the group ##STR2## which may be a free carboxylic acid or derivative thereof; the process comprising reacting a sulfate ester of formula II, wherein Q is a cation, with a compound of formula III, wherein L is a leaving group ##STR3## and hydrolyzing the sulfate ester formed. Preferably the sulfate ester of formula II is prepared by the oxidation of a phenol of formula IV with a persulfate. ##STR4##
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