Process for preparing rapidly disintegrating granulates
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United States of America Patent
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Jun 20, 1989
Grant Date -
N/A
app pub date -
Feb 17, 1987
filing date -
Feb 14, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to a process for preparing a rapidly disintegrating core granulate containing a pharmaceutically active compound, which granulate is optionally intended to be coated with a release determining coating, as well as such cores, whereby one adds a pharmaceutically active compound, optionally together with an emulsifier, to a solvent, and optionally treats the composition obtained intensively, optionally while reducing its particle size, distributes the treated composition obtained over a bed of a solid, preferably water soluble material, and dries the agglomerates thus obtained to the so as to form a rapidly disintegrating core granulate.
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