Automatic chemical analysis reagent distribution and analysis apparatus

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 4844868
SERIAL NO

06872814

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

An analysis apparatus is disclosed, which comprises guide rails for supporting a plurality of sample-containing reaction tubes in a straight row, a plunger for moving the reaction tubes supported on the guide rails in the direction of arrangement, a first rotary table for supporting a plurality of sample-containing reaction tubes along a circular line, and a motor for rotating the rotary table. Second rotary tables are disposed above the straight and circular arrangements of reaction tubes. These second rotary tables support at least two reagent distributors for distributing reagent into the reaction tubes. Each reagent distributor includes a reagent phial containing a reagent and a pump integral with the reagent phial for withdrawing the reagent in the reagent vessel. The pump has a nozzle through which the reagent is discharged. The rotary table is rotated by a motor such that the nozzle of a reagent distributor used for reagent distribution is brought to a position right above a pertinent reaction tube. The pump of the reagent distributor used for the reagent distribution is driven by a plunger.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
KABUSHIKI KAISHA TOSHIBATOKYO20986

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rokugawa, Kyuji Tochigi, JP 10 188

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 4456152 Measuring and dispensing apparatus 24 1982
 
Tokyo Shibaura Denki Kabushiki Kaisha (1)
* 4664885 Automatic chemical analyzer 7 1984
 
Beckman Instruments, Inc. (1)
* 4322216 Method and apparatus for positioning cars in a sample handling apparatus 49 1981
 
SALUS Ricerca e Sviluppo di CROCE' Dr. Francesco & C. Snc (1)
* 4501491 Device for optical indication of the phenomena of coagulation of blood, concentration and aggregation of blood platelets, or the like 15 1982
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
* 6120733 Self-contained assay device 28 1997
* 2002/0106,803 Handling method of body fluid sample and analysis apparatus using the same 0 2002
* 2011/0143,393 AUTOMATIC DEVICE FOR CARRYING OUT DETECTION REACTIONS, AND METHOD FOR DOSING REAGENTS ONTO MICROSCOPE SLIDES 1 2009
 
PHARMACOPEIA, LLC (1)
* 6365412 Centrifugal dispenser and method of use 6 2000
 
HITACHI CHEMICAL DIAGNOSTICS INC. (1)
* 2002/0164,807 Diagnostic instrument having overlapping carousels 6 2001
 
CHIRON DIAGNOSTICS CORPORATION (1)
* 6066300 Reagent handling system and configurable vial carrier for use therein 25 1998
 
P B Diagnostic Systems, Inc. (1)
* 5332549 Assay module transport apparatus for use in an automated analytical instrument 113 1992
 
NASCENT BIOSCIENCES, INC. (1)
6620383 Microvolume liquid dispensing device 5 2000
 
NORGREN LIMITED (1)
* 2008/0135,583 Liquid Dispensing System 9 2005
 
HITACHI, LTD. (6)
* 6599477 Chemical analysis apparatus 6 1998
* 6193933 Automatic analysis apparatus 44 1998
* 7204961 Liquid feed apparatus and automatic analyzing apparatus 0 1999
* 6197255 Chemical analyzing apparatus 16 1999
* 7105351 Handling method of body fluid sample and analysis apparatus using the same 4 2002
* 6924152 Handling method of body fluid sample and analysis apparatus using the same 8 2002
 
VENTANA MEDICAL SYSTEMS, INC. (21)
* 5232664 Liquid dispenser 127 1991
* 5595707 Automated biological reaction apparatus 219 1994
* 5654199 Method for rinsing a tissue sample mounted on a slide 128 1995
* 5654200 Automated slide processing apparatus with fluid injector 165 1995
* 5650327 Method for mixing reagent and sample mounted on a slide 158 1995
* 6352861 Automated biological reaction apparatus 159 1999
7118918 Automated biological reaction method 17 2001
6943029 Automated biological reaction apparatus 123 2002
* 2002/0072,122 Automated biological reaction apparatus 25 2002
6827901 Automated biological reaction apparatus 93 2002
7270785 Automated molecular pathology apparatus having fixed slide platforms 33 2002
7303725 Automated high volume slide staining system 55 2003
7378055 Automated molecular pathology apparatus having fixed slide platforms 50 2003
* 2003/0203,493 Automated molecular pathology apparatus having fixed slide platforms 30 2003
7470541 Automated biological reaction apparatus 20 2004
* 2005/0153,453 Automated biological reaction apparatus 15 2004
7468161 Automated high volume slide processing system 35 2005
8663991 Automated high volume slide processing system 1 2005
7404927 Automated molecular pathology apparatus having fixed slide platforms 31 2005
8048373 Automated high volume slide staining system 4 2007
9528918 Automated high volume slide processing system 0 2013
 
COGENT SYSTEMS, INC. (1)
* 2010/0178,204 Automated Self-Contained Liquid Handling and Detection System Device 4 2007
 
GEN-PROBE INCORPORATED (45)
6605213 Method and apparatus for performing a magnetic separation purification procedure on a sample solution 124 2000
6764649 Transport mechanism 74 2001
7033820 Automated system for isolating and amplifying a target nucleic acid sequence 39 2001
6890742 Automated process for isolating and amplifying a target nucleic acid sequence 94 2001
7267795 Incubator for use in an automated diagnostic analyzer 57 2002
7135145 Device for agitating the fluid contents of a container 38 2002
7118892 Automated process for preparing and amplifying a target nucleic acid sequence 40 2002
7384600 Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer 10 2002
7396509 Instrument for detecting light emitted by the contents of a reaction receptacle 13 2003
7560255 Automated process for detecting the presence of a target nucleic acid in a sample 34 2004
7666681 Method for agitating the fluid contents of a container 17 2005
7560256 Automated process for detecting the presence of a target nucleic acid in a sample 28 2005
7524652 Automated process for detecting the presence of a target nucleic acid in a sample 29 2005
7482143 Automated process for detecting the presence of a target nucleic acid in a sample 29 2005
8615368 Method for determining the amount of an analyte in a sample 6 2006
8008066 System for performing multi-formatted assays 43 2006
7964413 Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay 24 2006
7932081 Signal measuring system for conducting real-time amplification assays 8 2006
7897337 Method for performing multi-formatted assays 10 2006
7794659 Signal measuring system having a movable signal measuring device 9 2006
7547516 Method for reducing the presence of amplification inhibitors in a reaction receptacle 1 2006
8012419 Temperature-controlled incubator having rotatable door 5 2007
8137620 Temperature-controlled incubator having an arcuate closure panel 3 2007
9598723 Automated analyzer for performing a nucleic acid-based assay 0 2007
8337753 Temperature-controlled incubator having a receptacle mixing mechanism 2 2007
8318500 Method for agitating the contents of a reaction receptacle within a temperature-controlled environment 3 2007
8192992 System and method for incubating the contents of a reaction receptacle 17 2007
7666602 Method for agitating the fluid contents of a container 22 2007
8309358 Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment 2 2007
7638337 System for agitating the fluid contents of a container 5 2007
8569019 Method for performing an assay with a nucleic acid present in a specimen 1 2007
8569020 Method for simultaneously performing multiple amplification reactions 2 2008
8546110 Method for detecting the presence of a nucleic acid in a sample 1 2008
8440429 Method for detecting the presence of a nucleic acid in a sample 0 2008
8501461 System for performing multi-formatted assays 12 2009
8663922 Systems and methods for detecting multiple optical signals 1 2010
8349564 Method for continuous mode processing of the contents of multiple reaction receptacles in a real-time amplification assay 13 2010
9372156 System for processing contents of a receptacle to detect an optical signal emitted by the contents 1 2011
9046507 Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure 0 2011
8221682 System for incubating the contents of a reaction receptacle 2 2011
8718948 Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector 0 2012
8709814 Method for incubating the contents of a receptacle 0 2012
8883455 Method for detecting the presence of a nucleic acid in a sample 1 2013
9726607 Systems and methods for detecting multiple optical signals 0 2014
9150908 Method for detecting the presence of a nucleic acid in a sample 1 2014
 
Molecular Bio-Products, Inc. (1)
8080218 Metering doses of sample liquids 2 2009
 
BIOCEM IMMUNOSYSTEMS, LLC (1)
* 5698450 Method for measuring antigens or antibodies in biological fluids 90 1995
 
ORTHO-CLINICAL DIAGNOSTICS, INC. (3)
7250303 Chemistry system for a clinical analyzer 16 2002
7855084 Chemistry system for clinical analyzer 8 2007
* 2008/0145,939 Chemistry system for clinical analyzer 9 2007
 
CLINICAL DIAGNOSTIC SYSTEMS INC. (2)
* 5273717 Self-calibrating analyzer aspirator 10 1992
* 5344610 Aspirator probe with long pivot arm to minimize tip flick 11 1993
 
AKZO N.V. (1)
* 5236666 Temperature regulation in a sample handling system for an optical monitoring system 32 1992
 
ROCHE DIAGNOSTICS CORPORATION (4)
* 5384094 Diagnostic processing station 59 1993
* 5496519 Diagnostic processing station 12 1994
* 5762872 Apparatus for chemical and biochemical analysis of samples 55 1997
* 6106781 Conveying system for analytical samples 21 1997
 
MOLECULAR BIOPRODUCTS, INC. (6)
6706538 Microvolume liquid dispensing array 30 2000
7459128 Microfluidic mixing and dispensing 2 2004
* 2004/0208,794 Microfluidic mixing and dispensing 12 2004
7592185 Metering doses of sample liquids 1 2004
* 2005/0181,519 Metering doses of sample liquids 14 2004
8043865 Metering doses of sample liquids 2 2010
 
MITUTOYO CORPORATION (1)
* 2005/0238,248 Image processing apparatus using morphology 1 2005
 
ILLUMINA, INC. (13)
* 6663832 Oligonucleotide synthesizer 34 2000
* 2002/0028,159 Oligonucleotide synthesizer 2 2000
* 7390459 Oligonucleotide synthesizer 13 2001
* 2002/0044,894 Oligonucleotide synthesizer 9 2001
7914739 Continuous polymer synthesizer 1 2006
* 2007/0117,178 Continuous polymer synthesizer 8 2006
* 2007/0110,638 Continuous polymer synthesizer 6 2006
* 2009/0023,605 OLIGONUCLEOTIDE SYNTHESIZER 7 2008
9073033 Methods and compositions for processing chemical reactions 0 2011
8465694 Oligonucleotide synthesizer 0 2011
8731721 Continuous polymer synthesizer 0 2011
* 2011/0136,696 CONTINUOUS POLYMER SYNTHESIZER 1 2011
9649614 Methods and compositions for processing chemical reactions 0 2015
 
Biochemical Diagnostics, Inc. (1)
* 5585068 Apparatus for automatically separating a compound from a plurality of discrete liquid specimens 86 1994
 
ABBOTT LABORATORIES (7)
6588625 Sample handling system 17 2001
7458483 Assay testing diagnostic analyzer 12 2003
* 2004/0134,750 Assay testing diagnostic analyzer 36 2003
8535624 Assay testing diagnostic analyzer 2 2006
* 2007/0010,019 Assay testing diagnostic analyzer 6 2006
9656266 Assay testing diagnostic analyzer 0 2008
* 2008/0190,735 ASSAY TESTING DIAGNOSTIC ANALYZER 10 2008
 
TRINITY BIOTECH MANUFACTURING LIMITED AND TRINITY BIOTECH, PLC (1)
* 5646046 Method and instrument for automatically performing analysis relating to thrombosis and hemostasis 91 1995
 
DAKO DENMARK A/S (11)
* 5947167 Dispensing assembly with interchangeable cartridge pumps 113 1997
* 6092695 Interchangeable liquid dispensing cartridge pump 103 1998
6180061 Moving platform slide stainer with heating elements 103 1998
6244474 Interchangeable liquid dispensing cartridge pump 36 2000
7718435 Automated slide stainer with slide housing 11 2000
* 2004/0191,128 Slide stainer with heating 31 2004
7217392 Random access slide stainer with independent slide heating regulation 24 2004
* 2006/0147,351 Diaphram metering chamber dispensing systems 11 2004
* 2004/0241,050 Random access slide stainer with independent slide heating regulation 0 2004
7553672 Random access slide stainer with independent slide heating regulation 15 2007
* 2007/0281,364 Random access slide stainer with independent slide heating regulation 2 2007
 
AVENTIS PHARMACEUTICALS INC. (1)
* 2004/0033,554 Automated semi-solid matrix assay and liquid handler apparatus for the same 14 2003
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (3)
* 5609822 Reagent handling system and reagent pack for use therein 29 1995
* 5717148 Analysis instrument having carrier with liquid receiving wells 12 1996
* 5788928 Reagent handling system and reagent pack for use therein 31 1996
 
PWRISTINE, INC. (2)
* 2010/0025,432 WRISTBAND-MOUNTED DISPENSER FOR LIQUIDS AND POWDERS WITH AN IMPROVED DISPENSING MECHANISM 2 2008
* 2009/0014,475 WRISTBAND-MOUNTED DISPENSER FOR LIQUIDS AND POWDERS WITH AN IMPROVED DISPENSING MECHANISM 2 2008
 
ABBOTT LABORATORIES (2)
9057714 Reagent and sample handling device for automatic testing system 3 2009
* 2010/0111,765 REAGENT AND SAMPLE HANDLING DEVICE FOR AUTOMATIC TESTING SYSTEM 4 2009
 
The United States of America as represented by the Secretary of the Navy (1)
* 5061857 Waveguide-binding sensor for use with assays 50 1990
 
Societe Alcyon Analyzer S.A. (1)
* 5456882 Reaction segment for an automatic sample analyzer 24 1992
 
Microvol Limited (1)
* 4988482 Method and apparatus for chemical analysis 36 1988
* Cited By Examiner