Method for reducing skin irritation associated with drug/penetration enhancer compositions
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United States of America Patent
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Aug 8, 1989
Grant Date -
N/A
app pub date -
Sep 6, 1988
filing date -
Sep 6, 1988
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A composition and method for reducing the skin irritation properties of a transdermal drug/enhancer composition which comprises incorporating into said composition, either prior to or at the time of application the skin, an effective amount of glycerin. When incorporated into the drug/enhancer composition prior to application to the skin the glycerin content will be between about 0.1 and 70 wt. %, preferably between about 1.0 and 50 wt. % and most preferably between about 5.0 and 20 wt. % of the composition.
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