Hematoporphyrin derivative and method of preparation and purification

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United States of America Patent

PATENT NO 4861876
SERIAL NO

06935269

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Abstract

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A substance effective for treatment of tumors having a fluorescent emission between 640 nm and 650 nm capable of preferentially localizing in and being retained in tumor cells, the substance being a product of esterification of hematorporphyrin with a chlorin and a process for destruction of tumor cells in a patient involving the steps of: (a) injecting a solution containing the substance into a patient; (b) allowing the substance to accumulate in the tumor cells; and (c) irradiating the tumor site with light at a predetermined intensity and a wavelength between about 640 nm and about 650 nm.

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Patent Owner(s)

Patent OwnerAddress
WAYNE STATE UNIVERSITY A CORP OF MIDETROIT MI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kessel, David Detroit, MI 6 60

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