Pharmaceutical use of derivatives of tryptophan
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United States of America Patent
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Sep 26, 1989
Issued Date -
N/A
app pub date -
Jul 11, 1988
filing date -
Dec 12, 1984
priority date (Note) -
Expired
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Abstract
N-acylated derivatives of L-tryptophan of general formula (I), ##STR1## in which R is selected from the group consisting of: (a) a phenyl group, mono-substituted or di-substituted in the meta and para positions with halogens, linear or branched alkyl groups containing from 1 to 9 carbon atoms, the cyano group or the trifluoromethyl group, (b) a benzyloxy group, mono-substituted or di-substituted in the meta and para position with substituents selected from those indicated at (a), and (c) a benzydryloxy group. The derivatives are used in therapy, particularly for human pain relief, in the treatment of pathological conditions of the central nervous system and of pathological intestinal conditions.
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