Probes and methods for detecting activated ras oncogenes

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United States of America Patent

PATENT NO 4871838
SERIAL NO

06758104

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Abstract

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Molecules complementary to nucleotide sequences encoding mutant ras protiens which contain a single-base mutation in the codon encoding amino acids at position 13, 12 or 61 have been produced. These molecules are useful in methods of detecting specific single-base mutations in altered ras genes and the specific cancers associated with such mutations.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF RIJKS UNIVERSITTEIT LEIDEN THE WASSENAARSEWEG 72 2333 AL LEIDEN THE NETHERLANDS A PUBLIC BODY OF THE NETHERLANDSNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bos, Johannes L Leiden, NL 3 91
Van, der Eb Alex J Oegstgeest, NL 10 134

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