Suppository preparation having excellent absorption property
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United States of America Patent
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Oct 10, 1989
Grant Date -
N/A
app pub date -
Mar 8, 1982
filing date -
Jan 14, 1982
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A preparation containing an absorption promoter selected from N-acyl amino acid derivatives or N-acyl peptide derivatives represented by the formula: R-CO-A (R is an aliphatic hydrocarbon group, an aromatic hydrocarbon group or an aryl-substituted lower hydrocarbon group which may optionally be substituted, and A is an amino acid residue or a peptide residue), preferably in the presence of a salt at a concentation exhibiting higher osmotic pressure than isotonic sodium chloride solution, and a medicine is found to promote absorption of the medicine through a gastrointestinal organ such as the colon and rectum, and through the vagina.
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