Trifluoro acetyl-cyano-aniline intermediates for dopamine-.beta.hydroxylase inhibitors

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United States of America Patent

PATENT NO 4873357
SERIAL NO

07105628

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Abstract

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Potent dopamine-.beta.-hydroxylase inhibitors having the Formula: ##STR1## which are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.

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Patent Owner(s)

Patent OwnerAddress
SMITHKLINE BECKMAN CORPORATIONPHILADELPHIA PA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kaiser, Carl Haddon Heights, NJ 29 146
Kruse, Lawrence I Haddonfield, NJ 51 489
Ross, Stephen T Berwyn, PA 13 34

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