Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
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United States of America Patent
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Oct 24, 1989
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app pub date -
May 18, 1988
filing date -
May 22, 1987
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Abstract
A method of inactivating pathogens in proteinaceous biological and pharmaceutical products which comprises: mixing the product in an aqueous solution with one or more primary stabilizers selected from the group consisting of sugars and sugar alcohols and one or more secondary stabilizers selected from the group consisting of sodium acetate, potassium acetate, lithium acetate, magnesium acetate, ammonium acetate, barium acetate, sodium sulfate, ammonium sulfate, lithium sulfate, potassium sulfate and magnesium sulfate; and subjecting said aqueous solution to a pathogen inactivating process.
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