Phosphonic acid substituted aromatic steroids as inhibitors of steroid 5-.alpha.-reductase
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United States of America Patent
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Nov 21, 1989
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N/A
app pub date -
Dec 23, 1988
filing date -
Dec 23, 1988
priority date (Note) -
Expired
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Abstract
Invented are phosphonic acid substituted analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase, including using these compounds to reduce or maintain prostate size. Also invented are intermediates used in preparing these compounds.
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