Diuretic composition
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United States of America Patent
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-
Dec 19, 1989
Grant Date -
N/A
app pub date -
Jan 15, 1988
filing date -
Jan 15, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The present invention relates to a multiple-unit dose composition comprising furosemide as pharmaceutically active compound, whereby the composition gives a release of furosemide in accordance with Dissotest in a buffer having pH 1.5 of at most 4% during hour 1, a release in a buffer having pH 5.5 of at most 7.5% during a consecutive hour (hour 2), a release of furosemide in a buffer having pH 7.5 of at least 65% during a further consecutive hour (hour 3), and a release of furosemide in a buffer having pH 7.5 of at least 90% during a consecutive hour (hour 4).
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