Inductive collagen-based bone repair preparations
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United States of America Patent
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Dec 19, 1989
Issued Date -
N/A
app pub date -
Sep 25, 1987
filing date -
Oct 24, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An improved process for the preparation of mineral/collagen/OF (osteogenic factor) inductive implants for bone repair utilizes drying, under ambient pressure conditions, a suspension of 75-95% mineral particles, 5-25% collagen, and an effective amount of OF, such as 0.5-4% partially purified OFE or its equivalent wherein the concentration of collagen in the suspension subjected to drying is 30-100 mg/ml. The resulting implants are improved. They are homogeneous in composition and have a high compressive modulus as well as containing OF in a biologically active and available form.
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