Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists
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United States of America Patent
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Dec 26, 1989
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N/A
app pub date -
Apr 6, 1987
filing date -
Sep 23, 1985
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Expired
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Abstract
A potent, selective opioid receptor agonist or antagonist exhibiting properties useful for a longacting analgesic or opiate abuse treatment agent or appetite suppressant having the general formula: ##STR1## wherein R is methyl, cyclopropylmethyl or allyl, and R.sub.1 is an unsubstituted or substituted aryl, aralkyl, heteroaryl, heteroaralkyl or a cycloalkyl group with or without a heteroatom like S,O,N; and the pharmaceutically acceptable salts thereof.
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