Erythrocyte agglutination assay
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United States of America Patent
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Jan 16, 1990
Issued Date -
N/A
app pub date -
Jan 13, 1988
filing date -
Sep 17, 1987
priority date (Note) -
Expired
status (Latency Note)
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Abstract
In an erythrocyte agglutination assay, the agglutination reagent comprises at least one erythrocyte binding molecule coupled to at least one specific analyte binding molecule wherein the erythrocyte binding molecule does not cause agglutination when incubated with erythrocytes in the absence of analyte. Preferably, the erythrocytes are endogenous to the blood sample to be tested, that is, a whole blood sample is assayed. Mixtures of conjugates and conjugates of analyte analogues with erythrocyte binding molecules may also be used as agglutination reagents. The reagents and their use in direct or indirect assays is disclosed.
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