Nitrosothiols as hypotensive agents
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United States of America Patent
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Feb 13, 1990
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N/A
app pub date -
Aug 5, 1988
filing date -
Aug 5, 1988
priority date (Note) -
Expired
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Abstract
Systemic arterial pressure of an animal is decreased by administering directly to the animal an S-nitroso therapeutic compound, and particularly any of the S-nitrosoglutathione, D-(S-nitroso)-3-mercaptomethylpropionyl-L-proline, or S-nitrosothiol serum albumin in a dosage amount effective for a desired decrease and being an amount preferably between about 7 to 10 .mu.g/kg. animal weight/minute.
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