Transplantable artificial tissue
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United States of America Patent
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Feb 20, 1990
Issued Date -
N/A
app pub date -
Nov 6, 1987
filing date -
Aug 26, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A transplantable artificial tissue matrix structure containing viable cells which is suitable for insertion into the body is made by polymerizing precursors in an aqueous solution to form a shape retaining solid matrix comprising viable cells, matrix polymer and reversible gel polymer. The solution contains a matrix polymer precursor, a reversible gel polymer precursor, and viable cells. The reversible gel polymer is dissolved and removed to yield an insoluble, porous matrix containing viable cells. The conditions and reagents are selected to maintain the viability of the cells. The invention is particularly suitable for artificial transplant matrix tissue containing pancreatic islet cells.
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