Use of demineralized bone matrix in the repair of segmental defects
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United States of America Patent
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Feb 20, 1990
Issued Date -
N/A
app pub date -
Oct 29, 1987
filing date -
Oct 29, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A grafting material comprising milled bone which has an initial coating of guanidine-extracted bone proteins which are dialyzed from solution. Unbound bone proteins are removed and this augmented milled bone is lyophized. A subsequent coat of anti-coagulated plasma containing plasma proteins is applied to the augmented milled bone. The unbound plasma proteins are removed from the coating by rinsing.
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