Method and compositions useful in preventing equine influenza
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United States of America Patent
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Apr 24, 1990
Issued Date -
N/A
app pub date -
Jul 21, 1986
filing date -
Jun 20, 1985
priority date (Note) -
Expired
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Abstract
Recombinant vaccines for immunizing horses against equine influenza virus (EIV) are disclosed. The DNA sequences encoding the hemagglutinin (HA) and neuraminidase (NA) glycoproteins from the two strains of EIV currently infective in horses are used to construct vaccinia carried vaccines, to design synthetic peptides for primer and booster administration, and to permit recombinant synthesis of HA and/or NA protein based vaccines. These DNA sequences also provide probes useful for preparing similar vaccines from fresh isolates of new strains generated by genetic drift.
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