Polymer coated solid matrices and use in immunoassays
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United States of America Patent
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May 1, 1990
Grant Date -
N/A
app pub date -
Sep 29, 1987
filing date -
Sep 29, 1987
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Certain polyethyleneimines are used to coat solid carriers used in immunoassays to improve the sensitivity of the assay over what is obtained without the coating. Use of the invention in enzyme immunoassays yields sensitivities equal to that of radioimmunoassays. A post-coating is also used after the solid carrier has had a layer of capture molecule applied and before the assay is performed, to improve even further the sensitivity, reliability and dynamic range of the assay results.
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