Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents

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United States of America Patent

PATENT NO 4925677
SERIAL NO

07238802

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Abstract

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A biodegradable hydrogen matrix is provided, useful for the controlled release of pharmacologically active agents. The matrix is formed by cross-linking a proteinaceous component and a polysaccharide or mucopolysaccharide, and then loading a selected drug therein. By varying temperature, ionic strength, and the composition of the hydrogel matrix, one can control degradation kinetics, the degree of uptake of a particular pharmacologically active agent, and the overall timed release profile.

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Patent Owner(s)

  • WATSON PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Feijen, Jan Oude Grensweg, NL 29 1300

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