Expression of higher eucaryotic genes in aspergillus
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United States of America Patent
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Jun 19, 1990
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N/A
app pub date -
Jan 9, 1987
filing date -
Jan 17, 1986
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Abstract
A method for expressing higher eucaryotic genes in Aspergillus through the use of a recombinant plasmid capable of integration into the chromosomal DNA of Aspergillus is disclosed. It is preferred to utilize a transcriptional promoter within a DNA construct contained in the plasmid that is of a DNA sequence encoding an ADH enzyme or a TPI enzyme. Promoters capable of directing the expression of a heterologous gene in Aspergillus, as well as other filamentous fungal genera are also disclosed.
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