Therapy by vesicle delivery to the hydroxyapatite of bone
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United States of America Patent
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Jul 17, 1990
Grant Date -
N/A
app pub date -
Aug 25, 1988
filing date -
Aug 25, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A known procedure is used to prepare vesicles consisting of bipolar lipid membranes which are permeable and hence 'leak' their contents at a rate which is variable by choice. The vesicle is supplied with medication or diagnostic material and then attached to a target molecule conjugate that has affinity for the hydroxyapatite of bone. Thus, the vesicle clings to the skeleton structure and bathes the surrounding support surface with its contents for extended hours.
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