Reagent composition for fecal occult blood tests
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United States of America Patent
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Jul 17, 1990
Issued Date -
N/A
app pub date -
Mar 28, 1988
filing date -
Dec 11, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Fecal occult blood tests of enhanced sensitivity, specificity, and readability are provided by employing (1) a developer or complete reagent solution that uses as a solvent system a solvent comprising at least about 50% by volume of a solvent for iron protoporphyrins such as dimethyl sulfoxide and/or (2) a multi-chromagen comprised of a mixture of guaiac and ABTS. Test results may be further improved by incorporating hemoprotein solubilizing agents, plant peroxidase inhibitors, iron/copper chelating agents, accelerators and buffers in the developer/reagent.
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