Pharmaceutical delivery systems
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United States of America Patent
Stats
-
Jul 31, 1990
Grant Date -
N/A
app pub date -
Dec 17, 1987
filing date -
Dec 18, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac, flufenamic acid, flurbiprofen, ibuprofen, indomethacin, ketoprofen, naproxen, phenylbutazone, piroxicam and sulindac are administered in micelles to alleviate their adverse effects on the gastrointestinal tract. The drugs are formulated with surfactants such as polyethoxylated nonionics to give micelle-forming compositions.
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