1,3-dithian-2-ylidenes, their oxides, pharmaceutical compositions, and methods of use thereof

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United States of America Patent

PATENT NO 4946861
SERIAL NO

07271125

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the use of ketenethioacetals of the formula ##STR1## in which R.sub.1 represents aryl or heteroaryl, R.sub.2 represents hydrogen, an optionally substituted hydrocarbon radical, heteroaryl, an acyl radical, a group of the formula --S(O).sub.m --R.sub.a, wherein m is 0, 1 or 2 and R.sub.a is an optionally substituted hydrocarbon radical; or optionally functionally modified sulpho, A represents an optionally substituted bivalent aliphatic hydrocarbon radical and n is 0 or 1, and pharmaceutically acceptable salts of such compounds that contains a salt-forming group, for the treatment of liver diseases, respiratory tract diseases and vascular diseases pharmaceutical preparations containing compounds of the formula I and novel compounds of the formula I. The compounds have liver-protecting and immunomodulating properties.

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Patent Owner(s)

Patent OwnerAddress
ZYMA SAROUTE DE L'ETRAZ 1260 NYON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Narld, Philippe M Prangins, CH 1 3
Weith, Andre J Signy, CH 3 21

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