Method of preventing and treating pulmonary infection by fungi using aerosolized polyenes
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United States of America Patent
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Aug 21, 1990
Grant Date -
N/A
app pub date -
Aug 23, 1988
filing date -
Aug 23, 1988
priority date (Note) -
Expired
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Abstract
This invention concerns a method of preventing a pulmonary infection by a fungus in a subject susceptible to infection by the fungus comprising administering to the subject an amount per dose in an aerosol spray of a polyene or a pharmaceutically acceptable derivative thereof, effective to prevent pulmonary infection by the fungus. This invention further discloses a method of treating pulmonary aspergillosis in a subject comprising administering to the subject an amount per dose in an aerosol spray of a polyene, e.g., amphotericin B or pimaricin, or a pharmaceutically acceptable derivative thereof effective to treat aspergillosis.
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