Pharmaceutical tablet, pharmaceutical granulate and process for their preparation
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United States of America Patent
Stats
-
Aug 21, 1990
Grant Date -
N/A
app pub date -
Mar 2, 1988
filing date -
Mar 2, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A pharmaceutical tablet containing an amphoteric beta-lactam antibiotic, microcrystalline or micro fine cellulose or a mixture of both and a second disintegrant, being low-substituted hydroxypropylcellulose, which fully disintegrates in water within 60 seconds. When swallowed it shows a bioavailability as good as a pharmacy prepared suspension of the antibiotic. The tablet is compressed from a mixture containing a new granulate which is prepared from the antibiotic substance, microcrystalline and/or micro fine cellulose and water only. Such tablets can also be prepared by using other known tablet disintegrants as the second disintegrant.
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Family
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