Platinum compounds suitable for use as pharmaceuticals

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United States of America Patent

PATENT NO 4956459
SERIAL NO

07143763

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds of the formula: ##STR1## wherein each of R.sub.1 and R.sub.2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R.sub.1 and R.sub.2 together is a multifunctional carboxylic acid residue which forms a ring with the platinum atom through two oxygens of said multifunctional carboxylic acid; R.sub.3 is a deoxy mono or disaccharide or a derivative thereof; and R.sub.4 is selected from the group consisting of hydrogen, C.sub.1-4 -alkyl, phenyl, benzyl, substituted phenyl or substituted benzyl, wherein substituents are selected from the group consisting of halogen, nitro, C.sub.1-2 -alkoxy, carboxy, carbony ester or phenyl or a pharmaceutically acceptable salt thereof are disclosed. Compositions containing these compounds and methods using these compounds are also discussed.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE ONCOLOGY INCGAITHERSBURG MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Green, Dianna C Falls Church, VA 4 43
Hammer, Charles F Washington, DC 4 45
Schein, Philip S Bryn Mawr, PA 16 215
Talebian, Abdolhossen Herndon, VA 6 60

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